City : Ontario, Ontario, Canada

Category : Research & Development

Industry : Pharmaceutical

Employer : Lilly Canada

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Overview:

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

About POINT Biopharma:

POINT Biopharma Global Inc. is a globally focused radiopharmaceutical company building a platform for the clinical development and commercialization of radioligands that fight cancer. Recently acquired by Eli Lilly and Company, POINT aims to transform precision oncology by combining a portfolio of targeted radioligand assets, a seasoned management team, an industry-leading pipeline, in-house manufacturing capabilities, and secured supply for medical isotopes including actinium-225 and lutetium-177. POINT is a wholly owned subsidiary of Eli Lilly and Company.

Position Summary:

The individual will be supporting the discovery and development of radiolabeling reactions of both therapeutic and diagnostic radiolabeled compounds.  The individual will work collaboratively with internal team members and external partners to enable the supply of radiolabeled compounds for preclinical experiments.

Responsibilities:

·         Perform radiochemistry research and development for discovery stage programs

·         Produce and supply radiolabeled compounds to support preclinical evaluation of novel radioligands

·         As needed, develop new radiolabeling methods and formulations for discovery and preclinical stage programs

·         Synthesize, test and supply radiolabeled compounds for preclinical experiments

·         Provide onsite/remote technical support to external partners

·         Prepare and deliver presentations for internal and external team meetings

·         Author applicable laboratory notebook entries, development reports, manuscripts for publication in journals and patents

·         Other duties as assigned

Basic Requirements:

·         BS/MS/PhD degree in organic chemistry, chemistry or a related discipline

·         2 to 4 years of relevant experience in radiochemistry, radiopharmaceutical manufacturing, organic chemistry, process chemistry, inorganic chemistry

·         Proven ability to work independently with strong organization and excellent written/verbal communication skills

Additional Preferences:

·         Previous working experience in radiochemistry environment

·         Hands on experience with imaging radioisotopes (F-18, Ga-68, Cu-64, In-111, Zr-89) and/or therapeutic radioisotopes (Lu-177, Ac-225, Pb-212, Tb-161) is considered an asset

·         Experienced in quality control testing of radiopharmaceuticals (hands-on experience with radio-HPLC, radio-ITLC and GC)

·         Knowledge of environmental health and radioprotection requirements

·         Good working knowledge of multiple automated radiosynthesizer

·         Proven ability to work independently with strong organization and excellent written/verbal communication skills

·         Demonstrated ability to successfully prioritize projects and manage timelines in a fast paced environment

·         Functional Knowledge of GMPs and applicable FDA, EMA, Health Canada, USP, ICH and PDA guidelines

Physical Demands/Travel:

·         Requires up to 20% of travel nationally and internationally. A valid passport and eligiblity to travel into these countries are required.

·         Requires ability to lift up to 20 kg

·         Requires safety shoes and other personal protective equipment at applicable work area

 The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment:

·         This position’s work environment is in a Laboratory. Position requires to be onsite during the work week.

·         This role works in a hospital setting and it is mandatory for all employees to complete health screens before onboarding.  In the event the screen results show non-immunity, vaccines may need to be administered.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Eli Lilly Canada is committed to employment equity. We encourage applications from qualified women, members of visible minorities, aboriginal peoples, and persons with disabilities.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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