Director, Decision Science for Clinical Operations
City : Calgary
Category : Autre
Industry : Healthcare
Employer : GSK
Nom du site: UK – London – New Oxford Street, Belgium-Wavre, Mississauga Milverton Drive, UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence, Warsaw
Date de publication: Nov 4 2025
Date de publication: Nov 4 2025
Company Overview
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. GSK has kicked off 2025 with impressive growth in sales, profits, and earnings. We anticipate five major new FDA product approvals and 15 phase III/pivotal study readouts over the next two years. So far, we have secured two FDA approvals, with three more expected later this year. By uniting science, technology, and talent, we are committed to getting ahead of disease together.
Job Purpose
This is an exciting opportunity to channel your passion for innovation in the field of Statistics and Data Science to help shape the future of the Biostatistics function and transform the way in which GSK uses data and quantitative thinking to drive decision-making in R&D.
Biostatistics is the single-largest functional group of Statisticians, Programmers and Data Scientists within GSK R&D, numbering approx. 900 permanent people in the US, UK, Europe and India. Our mission is to put statistical thinking at the heart of R&D decision-making, to ensure that predictive models and well-designed experiments and trials deliver robust evidence as the input to those decisions, ultimately making the R&D process more efficient. We are investing in our cutting-edge innovation capabilities by expanding the Statistics & Data Science Innovation Hub (SDS-IH) led by Prof Nicky Best. The vision of SDS-IH is to be the catalyst for innovation and advanced data-driven decision making. In this role, you will work closely with SDS-IH to embed sophisticated analytics into Global Clinical Operations (GCO), enabling stakeholders to make timely, informed, and impactful decisions.
As the Director of Decision Science for Clinical Operations, you will serve as a strategic thought partner to senior R&D leadership, architecting the future of how GSK plans and executes clinical trials. Your mission is to embed sophisticated analytics and data-driven frameworks into the core of GCO. You will lead a high-performing decision science team to frame and model complex operational scenarios, quantify risks and trade-offs, and challenge assumptions. By translating analytical insights into clear, actionable strategies, you will drive decision quality and accelerate the delivery of new medicines to patients.
This position requires an on-site office presence for 2-3 days per week.
Key Responsibilities:
Strategic & Facilitative Leadership
Partner with GCO’s Decision Support team to lead high-stakes strategic discussions with clinical development leadership to frame complex business problems, develop differentiated options, and define clear analytical pathways.
Synthesize diverse evidence, including empirical data and expert judgment, to construct cohesive decision models that guide strategy.
Influence key investment and operational decisions by translating complex model outputs into compelling narratives and actionable recommendations for executive audiences.
Advanced Modeling & Analytics
Implement advanced decision models to quantify risk and identify value-add opportunities in study timelines and resource allocation.
Deliver robust predictive models for critical operational challenges, including patient recruitment, site performance, and milestone attainment, to create value optimal and risk-aware delivery strategies.
Identify and champion non-obvious value-add opportunities by applying innovative analytical approaches to complex clinical operations challenges.
Technical Innovation & Capability Development
Drive the design and deployment of scalable analytics solutions, including production-ready models, automated monitoring systems, and real-time data pipelines.
Champion best-in-class DevOps practices, including version control (Git), CI/CD pipelines, and automated testing to ensure robust, reproducible, and scalable solutions.
Train and mentor colleagues on the use of tools, methods, and structured decision frameworks to build organizational capability.
Why you?
Basic Qualifications:
PhD (preferred) or MSc in a quantitative field (e.g., Data Science, Statistics, Computer Science, Operations Research, Decision Analysis) with extensive experience in the pharmaceutical or biotech industry.
Proven expertise designing and building flexible decision models (e.g., Monte Carlo simulation, Bayesian analysis, scenario planning, sensitivity analysis) to quantify risk and value trade-offs.
Expertise in Python or R with the ability to write production-level code.
Hands-on experience with DevOps best practices, including Git, CI/CD, and testing.
Track record of leading and mentoring technical teams to deliver data science solutions with measurable business impact.
Exceptional communication and influencing skills, with the ability to distill complex analyses into compelling recommendations for senior leadership in a matrix environment.
Preferred Qualifications:
Deep knowledge of the drug development lifecycle and Clinical Operations workflows.
Therapeutic area depth, including knowledge of regulatory requirements and trial design.
Direct Clinical Operations experience.
Management consulting experience focused on pharmaceutical strategy or operations.
Expertise in advanced methods such as Bayesian statistics, machine learning, and enrollment simulation.
Company Overview
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. GSK has kicked off 2025 with impressive growth in sales, profits, and earnings. We anticipate five major new FDA product approvals and 15 phase III/pivotal study readouts over the next two years. So far, we have secured two FDA approvals, with three more expected later this year. By uniting science, technology, and talent, we are committed to getting ahead of disease together.
Job Purpose
This is an exciting opportunity to channel your passion for innovation in the field of Statistics and Data Science to help shape the future of the Biostatistics function and transform the way in which GSK uses data and quantitative thinking to drive decision-making in R&D.
Biostatistics is the single-largest functional group of Statisticians, Programmers and Data Scientists within GSK R&D, numbering approx. 900 permanent people in the US, UK, Europe and India. Our mission is to put statistical thinking at the heart of R&D decision-making, to ensure that predictive models and well-designed experiments and trials deliver robust evidence as the input to those decisions, ultimately making the R&D process more efficient. We are investing in our cutting-edge innovation capabilities by expanding the Statistics & Data Science Innovation Hub (SDS-IH) led by Prof Nicky Best. The vision of SDS-IH is to be the catalyst for innovation and advanced data-driven decision making. In this role, you will work closely with SDS-IH to embed sophisticated analytics into Global Clinical Operations (GCO), enabling stakeholders to make timely, informed, and impactful decisions.
As the Director of Decision Science for Clinical Operations, you will serve as a strategic thought partner to senior R&D leadership, architecting the future of how GSK plans and executes clinical trials. Your mission is to embed sophisticated analytics and data-driven frameworks into the core of GCO. You will lead a high-performing decision science team to frame and model complex operational scenarios, quantify risks and trade-offs, and challenge assumptions. By translating analytical insights into clear, actionable strategies, you will drive decision quality and accelerate the delivery of new medicines to patients.
This position requires an on-site office presence for 2-3 days per week.
Key Responsibilities:
Strategic & Facilitative Leadership
Partner with GCO’s Decision Support team to lead high-stakes strategic discussions with clinical development leadership to frame complex business problems, develop differentiated options, and define clear analytical pathways.
Synthesize diverse evidence, including empirical data and expert judgment, to construct cohesive decision models that guide strategy.
Influence key investment and operational decisions by translating complex model outputs into compelling narratives and actionable recommendations for executive audiences.
Advanced Modeling & Analytics
Implement advanced decision models to quantify risk and identify value-add opportunities in study timelines and resource allocation.
Deliver robust predictive models for critical operational challenges, including patient recruitment, site performance, and milestone attainment, to create value optimal and risk-aware delivery strategies.
Identify and champion non-obvious value-add opportunities by applying innovative analytical approaches to complex clinical operations challenges.
Technical Innovation & Capability Development
Drive the design and deployment of scalable analytics solutions, including production-ready models, automated monitoring systems, and real-time data pipelines.
Champion best-in-class DevOps practices, including version control (Git), CI/CD pipelines, and automated testing to ensure robust, reproducible, and scalable solutions.
Train and mentor colleagues on the use of tools, methods, and structured decision frameworks to build organizational capability.
Why you?
Basic Qualifications:
PhD (preferred) or MSc in a quantitative field (e.g., Data Science, Statistics, Computer Science, Operations Research, Decision Analysis) with extensive experience in the pharmaceutical or biotech industry.
Proven expertise designing and building flexible decision models (e.g., Monte Carlo simulation, Bayesian analysis, scenario planning, sensitivity analysis) to quantify risk and value trade-offs.
Expertise in Python or R with the ability to write production-level code.
Hands-on experience with DevOps best practices, including Git, CI/CD, and testing.
Track record of leading and mentoring technical teams to deliver data science solutions with measurable business impact.
Exceptional communication and influencing skills, with the ability to distill complex analyses into compelling recommendations for senior leadership in a matrix environment.
Preferred Qualifications:
Deep knowledge of the drug development lifecycle and Clinical Operations workflows.
Therapeutic area depth, including knowledge of regulatory requirements and trial design.
Direct Clinical Operations experience.
Management consulting experience focused on pharmaceutical strategy or operations.
Expertise in advanced methods such as Bayesian statistics, machine learning, and enrollment simulation.
#LI-GSK*
Pourquoi GSK?
Allier science, technologie et talent pour vaincre ensemble la maladie.
GSK est une entreprise biopharmaceutique mondiale dont la mission est de réunir la science, la technologie et le talent pour prendre ensemble de l'avance sur les maladies. Nous visons à avoir un impact positif sur la santé de 2,5 milliards de personnes d'ici la fin de la décennie, en tant qu'entreprise prospère et en croissance où les gens peuvent s'épanouir. Nous prenons de l'avance sur les maladies en les prévenant et en les traitant grâce à l'innovation dans les médicaments spécialisés et les vaccins. Nous nous concentrons sur quatre domaines thérapeutiques : les maladies respiratoires, l'immunologie et l'inflammation; l'oncologie; le VIH; les maladies infectieuses – pour avoir un impact à grande échelle sur la santé.
Les gens et les patients partout dans le monde comptent sur les médicaments et les vaccins que nous produisons; c'est pourquoi nous nous engageons à créer un environnement où nos employés peuvent s'épanouir et se concentrer sur ce qui compte le plus. Notre culture, qui repose sur l'ambition pour les patients, la responsabilité de la portée et le fait de faire ce qui est juste, constitue la base de la manière dont nous tenons nos engagements ensemble pour les patients, les actionnaires et nos employés.
GSK est un employeur garantissant l'égalité des chances. Cela garantit que tous les candidats qualifiés recevront une considération égale pour l'emploi sans distinction de race, de couleur, de religion, de sexe (y compris la grossesse, l'identité de genre et l'orientation sexuelle), de statut parental, d'origine nationale, d'âge, de handicap, d'informations génétiques (y compris les antécédents médicaux familiaux), de service militaire ou de toute autre base interdite par la loi fédérale, étatique ou locale.
Nous croyons en une culture de travail agile pour tous nos rôles. Si la flexibilité est importante pour vous, nous vous encourageons à explorer avec notre équipe de recrutement quelles sont les opportunités.
Si vous avez besoin d'ajustements à notre processus pour vous aider à démontrer vos forces et capacités, contactez-nous à UKRecruitment.Adjustments@gsk.com ou au 0808 234 4391. La ligne d'assistance est disponible de 8h30 à 12h00 du lundi au vendredi, pendant les jours fériés ces horaires et jours peuvent varier.
Veuillez noter que si votre demande ne concerne pas des ajustements, nous ne pourrons pas vous aider par ces canaux. Cependant, nous avons créé un guide FAQ sur le recrutement au Royaume-Uni. Cliquez sur le lien et faites défiler jusqu'à la section Carrières où vous trouverez des réponses à de nombreuses questions que nous recevons.
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